{"id":82680,"date":"2020-01-13T15:12:10","date_gmt":"2020-01-13T14:12:10","guid":{"rendered":"https:\/\/hemppedia.org\/przeglad-przeciwzapalnych-wlasciwosci-cbd\/"},"modified":"2021-10-28T17:15:10","modified_gmt":"2021-10-28T15:15:10","slug":"przeglad-przeciwzapalnych-wlasciwosci-cbd","status":"publish","type":"post","link":"https:\/\/old.hemppedia.org\/pl\/przeglad-przeciwzapalnych-wlasciwosci-cbd\/","title":{"rendered":"Przeciwzapalne w\u0142a\u015bciwo\u015bci CBD"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_57_1 counter-hierarchy ez-toc-counter ez-toc-white ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title ez-toc-toggle\" style=\"cursor: pointer\">Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\" role=\"button\"><label for=\"item-69f8be14a86d5\" ><span class=\"\"><span style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #428bca;color:#428bca\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #428bca;color:#428bca\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/label><input aria-label=\"Toggle\" aria-label=\"item-69f8be14a86d5\"  type=\"checkbox\" id=\"item-69f8be14a86d5\"><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/old.hemppedia.org\/pl\/przeglad-przeciwzapalnych-wlasciwosci-cbd\/#Czym_jest_stan_zapalny\" title=\"Czym jest stan zapalny?&nbsp;\">Czym jest stan zapalny?&nbsp;<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/old.hemppedia.org\/pl\/przeglad-przeciwzapalnych-wlasciwosci-cbd\/#CBD_moze_byc_skuteczny_w_leczeniu_stanow_zapalnych\" title=\"CBD mo\u017ce by\u0107 skuteczny w leczeniu stan\u00f3w zapalnych\">CBD mo\u017ce by\u0107 skuteczny w leczeniu stan\u00f3w zapalnych<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/old.hemppedia.org\/pl\/przeglad-przeciwzapalnych-wlasciwosci-cbd\/#Co_mowia_badania\" title=\"Co m\u00f3wi\u0105 badania\">Co m\u00f3wi\u0105 badania<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/old.hemppedia.org\/pl\/przeglad-przeciwzapalnych-wlasciwosci-cbd\/#Referencje\" title=\"Referencje\">Referencje<\/a><\/li><\/ul><\/nav><\/div>\n\n\n<div class=\"kk-star-ratings kksr-auto kksr-align-left kksr-valign-top\"\n    data-payload='{&quot;align&quot;:&quot;left&quot;,&quot;id&quot;:&quot;82680&quot;,&quot;slug&quot;:&quot;default&quot;,&quot;valign&quot;:&quot;top&quot;,&quot;ignore&quot;:&quot;&quot;,&quot;reference&quot;:&quot;auto&quot;,&quot;class&quot;:&quot;&quot;,&quot;count&quot;:&quot;3&quot;,&quot;legendonly&quot;:&quot;&quot;,&quot;readonly&quot;:&quot;&quot;,&quot;score&quot;:&quot;5&quot;,&quot;starsonly&quot;:&quot;&quot;,&quot;best&quot;:&quot;5&quot;,&quot;gap&quot;:&quot;4&quot;,&quot;greet&quot;:&quot;Rate post&quot;,&quot;legend&quot;:&quot;5\\\/5 - (3)&quot;,&quot;size&quot;:&quot;20&quot;,&quot;title&quot;:&quot;Przeciwzapalne w\\u0142a\\u015bciwo\\u015bci CBD&quot;,&quot;width&quot;:&quot;118&quot;,&quot;_legend&quot;:&quot;{score}\\\/{best} - ({count})&quot;,&quot;font_factor&quot;:&quot;1.25&quot;}'>\n            \n<div class=\"kksr-stars\">\n    \n<div class=\"kksr-stars-inactive\">\n            <div class=\"kksr-star\" data-star=\"1\" style=\"padding-right: 4px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 20px; height: 20px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"2\" style=\"padding-right: 4px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 20px; height: 20px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"3\" style=\"padding-right: 4px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 20px; height: 20px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"4\" style=\"padding-right: 4px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 20px; height: 20px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" data-star=\"5\" style=\"padding-right: 4px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 20px; height: 20px;\"><\/div>\n        <\/div>\n    <\/div>\n    \n<div class=\"kksr-stars-active\" style=\"width: 118px;\">\n            <div class=\"kksr-star\" style=\"padding-right: 4px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 20px; height: 20px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 4px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 20px; height: 20px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 4px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 20px; height: 20px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 4px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 20px; height: 20px;\"><\/div>\n        <\/div>\n            <div class=\"kksr-star\" style=\"padding-right: 4px\">\n            \n\n<div class=\"kksr-icon\" style=\"width: 20px; height: 20px;\"><\/div>\n        <\/div>\n    <\/div>\n<\/div>\n                \n\n<div class=\"kksr-legend\" style=\"font-size: 16px;\">\n            5\/5 - (3)    <\/div>\n    <\/div>\n\n<p><span style=\"font-weight: 400;\">D\u0142uga lista bada\u0144 i test\u00f3w medycznych ujawni\u0142a zdrowotne korzy\u015bci oleju CBD, w tym leczenie l\u0119k\u00f3w, stan\u00f3w zapalnych, <a href=\"https:\/\/hemppedia.org\/pl\/cbd-na-bezsennosc\/\" target=\"_blank\" rel=\"noreferrer noopener\">zaburze\u0144 snu<\/a>, \u0142agodzenie b\u00f3lu czy regulacj\u0119 ci\u015bnienia krwi<sup><a href=\"#footnote_0_82680\" id=\"identifier_0_82680\" class=\"footnote-link footnote-identifier-link\" title=\"Jadoon, K., Tan, G. and O&rsquo;Sullivan, S. (2017). A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study. JCI Insight, 2(12).\">1<\/a><\/sup>. Wed\u0142ug Harvard Medical School, CBD mo\u017ce by\u0107 stosowane w leczeniu dzieci\u0119cych zespo\u0142\u00f3w padaczkowych, takich jak Dravet i Lennox-Gaustaut<sup><a href=\"#footnote_1_82680\" id=\"identifier_1_82680\" class=\"footnote-link footnote-identifier-link\" title=\"Grinspoon, M. (2019). Cannabidiol (CBD) &mdash; what we know and what we don&rsquo;t &ndash; Harvard Health Blog. [online] Harvard Health Blog. Available at: https:\/\/www.health.harvard.edu\/blog\/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476.\">2<\/a><\/sup>.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Olej CBD do stosowania w stanach zapalnych zyska\u0142 r\u00f3wnie\u017c du\u017co na popularno\u015bci, poniewa\u017c wiele os\u00f3b jest coraz bardziej \u015bwiadomych skutk\u00f3w ubocznych lek\u00f3w. Dlatego wol\u0105 oni organiczne produkty, pozbawione powa\u017cnych niepo\u017c\u0105danych objaw\u00f3w, a takim produktem jest w\u0142a\u015bnie olej CBD<sup><a href=\"#footnote_2_82680\" id=\"identifier_2_82680\" class=\"footnote-link footnote-identifier-link\" title=\"Karimi, A., Majlesi, M. and Rafieian-Kopaei, M. (2015). Herbal versus synthetic drugs; beliefs and facts. Journal of Nephropharmacology, 4(1), pp.27&ndash;30.\">3<\/a><\/sup>.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Czym_jest_stan_zapalny\"><\/span><span style=\"font-weight: 400;\"><strong>Czym jest stan zapalny?&nbsp;<\/strong><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Stan zapalny, potocznie nazywany zapaleniem, jest zazwyczaj wywo\u0142ywany przez reakcj\u0119 uk\u0142adu odporno\u015bciowego na pocz\u0105tek infekcji lub reakcj\u0119 na obra\u017cenia. Zasadniczo jest to spos\u00f3b, w jaki organizm m\u00f3wi uk\u0142adowi odporno\u015bciowemu, aby rozpocz\u0105\u0142 proces gojenia i naprawy uszkodzonej tkanki cia\u0142a. Organizm u\u017cywa r\u00f3wnie\u017c zapalenia jako sposobu na obron\u0119 przed naje\u017ad\u017acami, takimi jak wirusy i bakterie.&nbsp;<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"CBD_moze_byc_skuteczny_w_leczeniu_stanow_zapalnych\"><\/span><span style=\"font-weight: 400;\"><strong>CBD mo\u017ce by\u0107 skuteczny w leczeniu<\/strong> <strong>stan\u00f3w zapalnych<\/strong><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">CBD i stan zapalny to dwa s\u0142owa, kt\u00f3re cz\u0119sto id\u0105 ze sob\u0105 w parze, poniewa\u017c CBD zosta\u0142o uznane za skuteczn\u0105 metod\u0119 leczenia stan\u00f3w zapalnych<sup><a href=\"#footnote_3_82680\" id=\"identifier_3_82680\" class=\"footnote-link footnote-identifier-link\" title=\"Burstein, S. (2015). Cannabidiol (CBD) and its analogs: a review of their effects on inflammation. Bioorganic &amp; Medicinal Chemistry, 23(7), pp.1377-1385.\">4<\/a><\/sup>. Oboj\u0119tnie czy zapalenie jest objawem choroby podstawowej lub jest chorob\u0105 sam\u0105 w sobie, CBD okaza\u0142 si\u0119 odgrywa\u0107 du\u017c\u0105 rol\u0119 terapeutyczn\u0105. Zgodnie z badaniami CBD walczy r\u00f3wnie\u017c z zapaleniem poprzez wywieranie efektu na makrofagi i kom\u00f3rki mikrogliali, kt\u00f3re s\u0105 odpowiedzialne za stan zapalny<sup><a href=\"#footnote_4_82680\" id=\"identifier_4_82680\" class=\"footnote-link footnote-identifier-link\" title=\"Nagarkatti, P., Pandey, R., Rieder, S., Hegde, V. and Nagarkatti, M. (2009). Cannabinoids as novel anti-inflammatory drugs. Future Medicinal Chemistry, 1(7), pp.1333-1349.\">5<\/a><\/sup>. CBD zmniejsza r\u00f3wnie\u017c przewlek\u0142y b\u00f3l zapalny zwi\u0105zany z zapaleniem, poprzez aktywacj\u0119 receptor\u00f3w glicynowych<sup><a href=\"#footnote_5_82680\" id=\"identifier_5_82680\" class=\"footnote-link footnote-identifier-link\" title=\"Xiong, W., Cui, T., Cheng, K., Yang, F., Chen, S., Willenbring, D., Guan, Y., Pan, H., Ren, K., Xu, Y. and Zhang, L. (2012). Cannabinoids suppress inflammatory and neuropathic pain by targeting &alpha;3 glycine receptors. The Journal of Experimental Medicine, 209(6), pp.1121-1134.\">6<\/a><\/sup>.&nbsp;<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">CBD mo\u017ce wi\u0119c pom\u00f3c w leczeniu takich dolegliwo\u015bci jak stany zapalne staw\u00f3w, <a href=\"https:\/\/hemppedia.org\/pl\/cbd-a-zapalenie-watroby\/\" target=\"_blank\" rel=\"noreferrer noopener\">zapalenie wirusowe w\u0105troby<\/a>, choroba <a href=\"https:\/\/hemppedia.org\/pl\/cbd-a-choroba-lesniowskiego-crohna\/\" target=\"_blank\" rel=\"noreferrer noopener\">Le\u015bniowskiego-Crohna<\/a>, <a href=\"https:\/\/hemppedia.org\/pl\/cbd-i-toczen\/\" target=\"_blank\" rel=\"noreferrer noopener\">tocze\u0144<\/a>, <a href=\"https:\/\/hemppedia.org\/pl\/cbd-i-leczenie-boreliozy\/\" target=\"_blank\" rel=\"noreferrer noopener\">borelioza<\/a>, zapalenie p\u0119cherza czy zapalenie p\u0142uc.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">CBD mo\u017ce by\u0107 te\u017c wykorzystywany r\u00f3wnie\u017c w leczeniu zapalenia mi\u0119\u015bnia sercowego<sup><a href=\"#footnote_6_82680\" id=\"identifier_6_82680\" class=\"footnote-link footnote-identifier-link\" title=\"Lee, W., Erdelyi, K., Matyas, C., Mukhopadhyay, P., Varga, Z., Liaudet, L., Hask&oacute;, G., \u010cih&aacute;kov&aacute;, D., Mechoulam, R. and Pacher, P. (2016). Cannabidiol Limits T Cell-Mediated Chronic Autoimmune Myocarditis: Implications to Autoimmune Disorders and Organ Transplantation. Molecular Medicine, 22(1), pp.136-146. [\">7<\/a><\/sup><\/span><span style=\"font-weight: 400;\">, kt\u00f3re pozostawione bez leczenia, powoduje udar m\u00f3zgu i jego uszkodzenia oraz innych chor\u00f3b uk\u0142adu kr\u0105\u017cenia. CBD sta\u0142o si\u0119 niezwykle popularne w leczeniu niekt\u00f3rych dolegliwo\u015bci, poniewa\u017c jest naturalne i bardzo skuteczne.<\/span><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Co_mowia_badania\"><\/span><span style=\"font-weight: 400;\"><strong>Co m\u00f3wi\u0105 badania<\/strong><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><span style=\"font-weight: 400;\">Badania nad olejem CBD i stanem zapalnym oraz zwi\u0105zanym z tym b\u00f3lem, przynios\u0142y ciekawe rezultaty<sup><a href=\"#footnote_7_82680\" id=\"identifier_7_82680\" class=\"footnote-link footnote-identifier-link\" title=\"Vu\u010dkovi\u0107, S., Srebro, D., Vujovi\u0107, K., Vu\u010deti\u0107, \u010c. and Prostran, M. (2018). Cannabinoids and Pain: New Insights From Old Molecules. Frontiers in Pharmacology, 9.\">8<\/a><\/sup> <sup><a href=\"#footnote_8_82680\" id=\"identifier_8_82680\" class=\"footnote-link footnote-identifier-link\" title=\"Baron, E. (2018). Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science. Headache: The Journal of Head and Face Pain, 58(7), pp.1139-1186.\">9<\/a><\/sup>. Wiele os\u00f3b, kt\u00f3re bra\u0142y udzia\u0142 w badaniach, by\u0142o w stanie zast\u0105pi\u0107 leki o powa\u017cnych skutkach ubocznych, do kt\u00f3rych organizm zd\u0105\u017cy\u0142 si\u0119 ju\u017c przyzwyczai\u0107, ca\u0142kowicie naturalnymi olejami CBD. Opr\u00f3cz walki z faktycznym stanem zapalnym, olej CBD mo\u017ce r\u00f3wnie\u017c z\u0142agodzi\u0107 b\u00f3l tak, aby stan zapalenia by\u0142 mniej uci\u0105\u017cliwy.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">W badaniu opublikowanym w British Journal of Pharmacology<sup><a href=\"#footnote_9_82680\" id=\"identifier_9_82680\" class=\"footnote-link footnote-identifier-link\" title=\"Costa, B., Giagnoni, G., Franke, C., Trovato, A. and Colleoni, M. (2004). Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation. British Journal of Pharmacology, 143(2), pp.247-250.\">10<\/a><\/sup> <\/span><span style=\"font-weight: 400;\">zbadano skuteczno\u015b\u0107 kannabidiolu w \u0142agodzeniu ostrego zapalenia u szczur\u00f3w i stwierdzono, \u017ce CBD mo\u017ce stanowi\u0107 u\u017cyteczn\u0105 farmakologiczn\u0105 alternatyw\u0119 w leczeniu ostrego zapalenia i b\u00f3lu.<\/span><\/p>\n\n\n\n<p><span style=\"font-weight: 400;\">Ponadto, badania przeprowadzone przez Uniwersytet w Mediolanie ujawni\u0142y, \u017ce niewielkie zapalenie by\u0142o r\u00f3wnie\u017c skutecznie leczone przez kannabidiol<sup><a href=\"#footnote_10_82680\" id=\"identifier_10_82680\" class=\"footnote-link footnote-identifier-link\" title=\"Costa, B., Trovato, A., Comelli, F., Giagnoni, G. and Colleoni, M. (2007). The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain. European Journal of Pharmacology, 556(1-3), pp.75-83.\">11<\/a><\/sup>.<\/span><\/p>\n\n\n\n<hr class=\"wp-block-separator\"\/>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Referencje\"><\/span><span style=\"font-weight: 400;\"><strong>Referencje<\/strong><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ol class=\"footnotes\"><li id=\"footnote_0_82680\" class=\"footnote\">Jadoon, K., Tan, G. and O\u2019Sullivan, S. (2017).<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5470879\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\"> A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study<\/span><\/a><span style=\"font-weight: 400;\">. <\/span><i><span style=\"font-weight: 400;\">JCI Insight<\/span><\/i><span style=\"font-weight: 400;\">, 2(12).<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_0_82680\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_1_82680\" class=\"footnote\">Grinspoon, M. (2019). <\/span><i><span style=\"font-weight: 400;\">Cannabidiol (CBD) \u2014 what we know and what we don\u2019t \u2013 Harvard Health Blog<\/span><\/i><span style=\"font-weight: 400;\">. [online] Harvard Health Blog. Available at: <\/span><a href=\"https:\/\/www.health.harvard.edu\/blog\/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.health.harvard.edu\/blog\/cannabidiol-cbd-what-we-know-and-what-we-dont-2018082414476<\/span><\/a><span style=\"font-weight: 400;\">.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_1_82680\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_2_82680\" class=\"footnote\">Karimi, A., Majlesi, M. and Rafieian-Kopaei, M. (2015). <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5297475\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Herbal versus synthetic drugs; beliefs and facts.<\/span><\/a><span style=\"font-weight: 400;\"> Journal of Nephropharmacology, 4(1), pp.27\u201330.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_2_82680\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_3_82680\" class=\"footnote\">Burstein, S. (2015). <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0968089615000838\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Cannabidiol (CBD) and its analogs: a review of their effects on inflammation<\/span><\/a><span style=\"font-weight: 400;\">. <\/span><i><span style=\"font-weight: 400;\">Bioorganic &amp; Medicinal Chemistry<\/span><\/i><span style=\"font-weight: 400;\">, 23(7), pp.1377-1385.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_3_82680\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_4_82680\" class=\"footnote\">Nagarkatti, P., Pandey, R., Rieder, S., Hegde, V. and Nagarkatti, M. (2009). <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2828614\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Cannabinoids as novel anti-inflammatory drugs.<\/span><\/a> <i><span style=\"font-weight: 400;\">Future Medicinal Chemistry<\/span><\/i><span style=\"font-weight: 400;\">, 1(7), pp.1333-1349.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_4_82680\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_5_82680\" class=\"footnote\">Xiong, W., Cui, T., Cheng, K., Yang, F., Chen, S., Willenbring, D., Guan, Y., Pan, H., Ren, K., Xu, Y. and Zhang, L. (2012). <\/span><a href=\"http:\/\/jem.rupress.org\/content\/209\/6\/1121.long\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Cannabinoids suppress inflammatory and neuropathic pain by targeting \u03b13 glycine receptors.<\/span><\/a> <i><span style=\"font-weight: 400;\">The Journal of Experimental Medicine<\/span><\/i><span style=\"font-weight: 400;\">, 209(6), pp.1121-1134.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_5_82680\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_6_82680\" class=\"footnote\"><\/span><span style=\"font-weight: 400;\">Lee, W., Erdelyi, K., Matyas, C., Mukhopadhyay, P., Varga, Z., Liaudet, L., Hask\u00f3, G., \u010cih\u00e1kov\u00e1, D., Mechoulam, R. and Pacher, P. (2016). <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26772776\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Cannabidiol Limits T Cell-Mediated Chronic Autoimmune Myocarditis: Implications to Autoimmune Disorders and Organ Transplantation<\/span><\/a><span style=\"font-weight: 400;\">. Molecular Medicine, 22(1), pp.136-146. [<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_6_82680\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_7_82680\" class=\"footnote\">Vu\u010dkovi\u0107, S., Srebro, D., Vujovi\u0107, K., Vu\u010deti\u0107, \u010c. and Prostran, M. (2018). <\/span><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphar.2018.01259\/full\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Cannabinoids and Pain: New Insights From Old Molecules<\/span><\/a><span style=\"font-weight: 400;\">. <\/span><i><span style=\"font-weight: 400;\">Frontiers in Pharmacology<\/span><\/i><span style=\"font-weight: 400;\">, 9. <span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_7_82680\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_8_82680\" class=\"footnote\">Baron, E. (2018). <\/span><a href=\"https:\/\/headachejournal.onlinelibrary.wiley.com\/doi\/full\/10.1111\/head.13345\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science<\/span><\/a><span style=\"font-weight: 400;\">. <\/span><i><span style=\"font-weight: 400;\">Headache: The Journal of Head and Face Pain<\/span><\/i><span style=\"font-weight: 400;\">, 58(7), pp.1139-1186.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_8_82680\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_9_82680\" class=\"footnote\"><\/span><span style=\"font-weight: 400;\">Costa, B., Giagnoni, G., Franke, C., Trovato, A. and Colleoni, M. (2004). <\/span><a href=\"https:\/\/bpspubs.onlinelibrary.wiley.com\/doi\/full\/10.1038\/sj.bjp.0705920\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation.<\/span><\/a> <i><span style=\"font-weight: 400;\">British Journal of Pharmacology<\/span><\/i><span style=\"font-weight: 400;\">, 143(2), pp.247-250.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_9_82680\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><li id=\"footnote_10_82680\" class=\"footnote\">Costa, B., Trovato, A., Comelli, F., Giagnoni, G. and Colleoni, M. (2007). <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S001429990601257X\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain.<\/span><\/a> <i><span style=\"font-weight: 400;\">European Journal of Pharmacology<\/span><\/i><span style=\"font-weight: 400;\">, 556(1-3), pp.75-83.<span class=\"footnote-back-link-wrapper\"> [<a href=\"#identifier_10_82680\" class=\"footnote-link footnote-back-link\">&#8617;<\/a>]<\/span><\/li><\/ol>","protected":false},"excerpt":{"rendered":"<p>D\u0142uga lista bada\u0144 i test\u00f3w medycznych ujawni\u0142a zdrowotne korzy\u015bci oleju CBD, w tym leczenie l\u0119k\u00f3w, stan\u00f3w zapalnych, zaburze\u0144 snu, \u0142agodzenie b\u00f3lu czy regulacj\u0119 ci\u015bnienia krwi1. Wed\u0142ug Harvard Medical School, CBD mo\u017ce by\u0107 stosowane w leczeniu dzieci\u0119cych zespo\u0142\u00f3w padaczkowych, takich jak Dravet i Lennox-Gaustaut2.&nbsp; Olej CBD do stosowania w stanach zapalnych zyska\u0142 r\u00f3wnie\u017c du\u017co na popularno\u015bci, [&hellip;]<\/p>\n","protected":false},"author":30,"featured_media":82566,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"no","_lmt_disable":"no","footnotes":""},"categories":[131],"tags":[],"acf":[],"modified_by":"Hemppedia","_links":{"self":[{"href":"https:\/\/old.hemppedia.org\/pl\/wp-json\/wp\/v2\/posts\/82680"}],"collection":[{"href":"https:\/\/old.hemppedia.org\/pl\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/old.hemppedia.org\/pl\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/old.hemppedia.org\/pl\/wp-json\/wp\/v2\/users\/30"}],"replies":[{"embeddable":true,"href":"https:\/\/old.hemppedia.org\/pl\/wp-json\/wp\/v2\/comments?post=82680"}],"version-history":[{"count":1,"href":"https:\/\/old.hemppedia.org\/pl\/wp-json\/wp\/v2\/posts\/82680\/revisions"}],"predecessor-version":[{"id":110497,"href":"https:\/\/old.hemppedia.org\/pl\/wp-json\/wp\/v2\/posts\/82680\/revisions\/110497"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/old.hemppedia.org\/pl\/wp-json\/wp\/v2\/media\/82566"}],"wp:attachment":[{"href":"https:\/\/old.hemppedia.org\/pl\/wp-json\/wp\/v2\/media?parent=82680"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/old.hemppedia.org\/pl\/wp-json\/wp\/v2\/categories?post=82680"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/old.hemppedia.org\/pl\/wp-json\/wp\/v2\/tags?post=82680"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}